Recent advances is enzymatic deprotection reactions of amino groups, carboxyl groups, thiol groups and hydroxyl groups are reviewed. Enzymatic deprotection techniques, which have the advantages of high selectivity, high specificity under mild conditions and in aqueous solutions, are being evaluated as potential methods for synthesizing the sensitive compounds such as peptide conjugates and carbohydrates.

Key words: ENZYME CATALYSIS, AMINO GROUP, CARBOXY GROUP, MERCAPTO GROUP, HYDROXY GROUP, BIOCATALYSIS, PROTECTIVE GROUP