Chinese Journal of Organic Chemistry ›› 2004, Vol. 24 ›› Issue (3): 310-314. Previous Articles     Next Articles

(3S)-2,2-二甲基-3-苄氧基癸酸的合成

孟祎a, 陈立功*,a, 许正双b, 许艳杰a   

  1. a 天津大学药物科学与技术学院 天津 300072
    b 天津大学化工学院 天津 300072
  • 收稿日期:2003-06-09 修回日期:2003-07-31 接受日期:2003-09-05 发布日期:2022-09-20
  • 基金资助:
    江苏省自然科学基金(No. 02KJB150008)资助项目

Synthesis of (3S)-3-Benzyloxy-2,2-dimethyl-decanoic Acid

MENG, Yia, CHEN, Li-Gong*,a, XU, Zheng-Shuangb, XU, Yan-Jiea   

  1. a School of Pharmaceutical Science Technology, Tianjin University, Tianjin 300072
    b School of Chemical Engineering, Tianjin University, Tianjin 300072
  • Received:2003-06-09 Revised:2003-07-31 Accepted:2003-09-05 Published:2022-09-20
  • Contact: *E-mail: xzsd-fcj@263.net

(3S)-3-Benzyloxy-2,2-dimethyl-decanoic acid was synthesized from (R)-pantolactone through reduction, hydroxy protection, cyclization, ring-opening, de-protection, oxidation, et al. in overall yield of 40.0%.

Key words: 2,2-dimethyl-3-hydroxy-decanoic acid, 2,2-dimethyl-3-benzyloxy-decanoic acid, epoxidation