Chinese Journal of Organic Chemistry ›› 2004, Vol. 24 ›› Issue (6): 673-674. Previous Articles     Next Articles

用Heck反应合成1-羟基-4-(3-吡啶基)丁-2-酮

蔡春*, 吕春绪   

  1. 南京理工大学化工学院 南京 210094
  • 收稿日期:2003-04-18 修回日期:2003-11-10 接受日期:2003-12-10 发布日期:2022-09-21
  • 通讯作者: *E-mail: caichunh@mail.njust.edu.cn

Synthesis of 1-Hydroxy-4-(3-pyridyl)butan-2-one Using Heck Reaction

CAI, Chun*, LÜ, Chun-Xu   

  1. School of Chemical Engineering, Nanjing University of Science & Technology, Nanjing 210094
  • Received:2003-04-18 Revised:2003-11-10 Accepted:2003-12-10 Published:2022-09-21

Under the Heck reaction condition with Ph3P as ligand, 1-hydroxy-4-(3-pyridyl)butan-2-one can be synthesized utilizing cross-coupling of 3-halopyridine and 3-butene-1,2-diol, and this methodology hasthe advantage of lower cost and wider diversity of raw material.

Key words: 1-hydroxy-4-(3-pyridyl)butan-2-one, Heck reaction, cross-coupling