Clean Synthesis of 3-Aroyl-2,4,6-triaryl-4-hydroxycyclohexane-1,1-dicarbonitrile in Aqueous Media

Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (02): 261-265. Previous Articles Next Articles

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水中2,4,6-三芳基-3-芳酰基-4-羟基环己基-1,1-二甲腈的洁净合成

靳通收*，尹影，刘利宾，赵莹，李同双

(河北大学化学与环境科学学院保定 071002)

收稿日期:2006-05-08 修回日期:2006-06-21 发布日期:2007-01-30
通讯作者: 靳通收

Clean Synthesis of 3-Aroyl-2,4,6-triaryl-4-hydroxycyclohexane-1,1-dicarbonitrile in Aqueous Media

JIN Tong-Shou*, YIN Ying, LIU Li-Bin, ZHAO Ying, LI Tong-Shuang

(College of Chemistry and Environmental Science, Hebei University, Baoding 071002)

Received:2006-05-08 Revised:2006-06-21 Published:2007-01-30
Contact: JIN Tong-Shou

Abstract

A series of 3-aroyl-2,4,6-triaryl-4-hydroxycyclohexane-1,1-dicarbonitriles were synthesized from chalcones and malononitrile catalyzed by hexadecyltriethyl ammonium bromide (3 mol%) in aqueous media. The structures of all products were characterized by ¹H NMR, IR spectra and elemental analysis. This method provides several advantages such as mild conditions, simple work-up procedure, high yields and environment friendliness. In addition, water was chosen as a green solvent.

Key words: malononitrile, aqueous media, chalcone, clean synthesis, 3-aroyl-2,4,6-triaryl-4-hydroxycyclohexane-1,1-dicarbonitrile

Cite this article

JIN Tong-Shou*, YIN Ying, LIU Li-Bin, ZHAO Ying, LI Tong-Shuang. Clean Synthesis of 3-Aroyl-2,4,6-triaryl-4-hydroxycyclohexane-1,1-dicarbonitrile in Aqueous Media[J]. Chin. J. Org. Chem., 2007, 27(02): 261-265.

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水中2,4,6-三芳基-3-芳酰基-4-羟基环己基-1,1-二甲腈的洁净合成

Clean Synthesis of 3-Aroyl-2,4,6-triaryl-4-hydroxycyclohexane-1,1-dicarbonitrile in Aqueous Media

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