Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (10): 1188-1194. Previous Articles     Next Articles

Review

功能性离子液体支载液相有机合成研究进展

胡燚*,李恒,黄和,韦萍   

  1. (南京工业大学制药与生命科学学院 南京 210009)
  • 收稿日期:2006-11-29 修回日期:2007-01-23 发布日期:2007-09-28
  • 通讯作者: 胡燚

Advance in Liquid-Phase Organic Synthesis Using Functional Ionic Liquid as Supports

HU Yi*,LI Heng,HUANG He,WEI Ping   

  1. (College of Life Science and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing 210009)
  • Received:2006-11-29 Revised:2007-01-23 Published:2007-09-28
  • Contact: HU Yi

This paper focuses on the concept and features of functional ionic liquid supported liquid-phase organic synthesis, and its application to the synthesis of small molecular heterocycles, peptides, oligosaccharides. The application of functional ionic liquid supported catalysts and reagents to liquid-phase organic synthesis is also described. As demonstrated in this paper, the functional ionic liquid could be used widely as novel soluble supports with high loading capacity in liquid-phase organic synthesis promoting the reactions effectively, simplifying the isolation operation, giving higher yields and selectivity as well.

Key words: liquid-phase organic synthesis, support, combinatory chemistry, ionic liquid