Synthesis of 2-Aryl-5-(6-pyridazinon-3-yl)-1,3,4-oxadiazoles

Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (04): 634-637. Previous Articles Next Articles

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2-芳基-5-(6-哒嗪酮-3-基)-1,3,4-噁二唑的合成

陶晶* ; 曹玲华

(a伊犁师范学院生命与资源环境系奎屯 833200)
(b新疆大学化学化工学院乌鲁木齐 830046)

收稿日期:1900-01-01 修回日期:1900-01-01 发布日期:2009-04-20
通讯作者: 陶晶

Synthesis of 2-Aryl-5-(6-pyridazinon-3-yl)-1,3,4-oxadiazoles

Tao, Jing*; Cao, Linghua

(a Department of Biology and Resource Environment, Yili Normal College, Kuitun 833200)
(b College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046)

Received:1900-01-01 Revised:1900-01-01 Published:2009-04-20
Contact: Tao, Jing

Abstract

The reaction of 1,4,5,6-tetrahydro-6-pyridazinone-3-carboxylic acid hydrazide (1) and 1,6-dihydro-6-pyridazinone-3-carboxylic acid hydrazide (2) with aromatic aldehydes afforded aromatic al-dehyde hydrazones 3a～3g and 5a～5g. A series of 1,3,4-oxadiazole derivatives 4a～4g and 6a～6g were obtained from 3a～3g and 5a～5g by the cyclization with bromine. Their structures were established by 1H NMR, IR, MS techniques and elemental analysis.

Key words: aromatic aldehyde hydrazone, pyridazinone, oxadiazole

Cite this article

Tao, Jing*; Cao, Linghua. Synthesis of 2-Aryl-5-(6-pyridazinon-3-yl)-1,3,4-oxadiazoles[J]. Chin. J. Org. Chem., 2009, 29(04): 634-637.

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2-芳基-5-(6-哒嗪酮-3-基)-1,3,4-噁二唑的合成

Synthesis of 2-Aryl-5-(6-pyridazinon-3-yl)-1,3,4-oxadiazoles

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