In order to find new thiazole lead compounds, thirty five N-(substituted-thiazole-2-yl)-chrysanthemumamides were synthesized from five types of chrysanthemic acids with seven substituted 2-amino-thiazols. The structures of all new compounds were confirmed by ¹H NMR, MS and elemental analysis. At the concentration of 600 mg/L, compound 3d, 6a, 6d, 4a, 4b, 4c, 4e showed insecticidal activity (100%) against Plutella xylostella Linnaeus. At the concentration of 50 mg/L, compound 3d and 7c possessed good fungicidal activity toward the tested pathogens. All compounds have shown no herbicidal activity.

Key words: N-(substituted-thiazole-2-yl)-chrysanthemumamide, insecticidal activity, fungicidal activity