Chin. J. Org. Chem. ›› 2011, Vol. 31 ›› Issue (04): 505-510. Previous Articles     Next Articles

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轴不安定性联苯类膦-噁唑啉配体/铱配合物在亚胺不对称氢化反应中的应用

姚冬梅,田丰涛,张万斌*   

  1. (上海交通大学化学化工学院 上海 200240)
  • 收稿日期:2010-08-10 修回日期:2010-11-23 发布日期:2010-11-23
  • 通讯作者: 张万斌 E-mail:wanbin@sjtu.edu.cn

Asymmetric Hydrogenation of Imines Catalyzed by Ir/Phosphine- oxazoline Complexes with an Axis-unfixed Biphenyl Backbone

YAO Dong-Mei, TIAN Feng-Tao, ZHANG Wan-Bin   

  1. (School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240)
  • Received:2010-08-10 Revised:2010-11-23 Published:2010-11-23

A series of Ir complexes with axis-unfixed phosphine-oxazoline ligands were applied as catalysts in the asymmetric hydrogenation of imines. It was found that these catalysts showed excellent catalytic activity (up to 99% conversion) and good enantioselectivity (up to 75% ee) for the reaction.

Key words: axial chirality, phosphine-oxazoline ligand, Ir complex, asymmetric hydrogenation, imine