Chin. J. Org. Chem. ›› 2001, Vol. 21 ›› Issue (10): 732-736. Previous Articles     Next Articles

距离比较法识别光系统Ⅱ电子传递抑制剂药效团模型

刘小兰;孙命;文欣;周卫红;杨霞;缪方明   

  1. 天津师范大学化学与生命科学学院.;天津理工学院化工系.天津( )
  • 发布日期:2001-10-25

Recognition of pharmacophore model of photosystem Ⅱ electronic transport inhibitory molecules with distance comparison method

Liu Xiaolan;Sun Ming;Wen Xin;Zhou Weihong;Yang Xia;Miao Fangming   

  1. Tainjin.;Tianjin College of Polytechnology, Dept of Chem Eng. Tianjin
  • Published:2001-10-25

A pharmacophore model was established based on the studies of CoMFA with nine different electron transport inhibiting molecules for the photosystem Ⅱ(PSⅡ) using the DISCO(Distance Comparison) method. The research result will be applied in the design novel lead compounds of PSⅡ inhibitors.

Key words: IDENTIFICATION, ELECTRON TRANSFER, INHIBITOR, PHOTOSYNTHESIS

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