Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (01): 20-33. Previous Articles     Next Articles

Review

印楝素的合成、结构修饰及生物活性研究进展

樊会丹a ; 张从海a ; 严胜骄a ; 林 军*,a,b   

  1. (a云南大学化学科学与工程学院 教育部自然资源药物化学重点实验室 昆明 650091)
    (b南开大学元素有机化学研究所元素有机化学国家重点实验室 天津 300071)
  • 收稿日期:2008-03-08 修回日期:2008-04-29 发布日期:2009-01-20
  • 通讯作者: 林 军

Advances of Synthesis and Structure Modification and Bioactivity of Azadirachtin

Fan, Huidana ; Zhang, Conghaia; Yan, Shengjiaoa ; Lin, Jun*,a,b   

  1. (a Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and
    Technology, Yunnan University, Kunming 650091)
    (b State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University,
    Tianjin 300071)
  • Received:2008-03-08 Revised:2008-04-29 Published:2009-01-20
  • Contact: Lin, Jun

Since azadirachtin was first isolated and identified, the general and unique bioactivities have attracted considerable research effort. It is an excellent botanical pesticide used widely in agriculture presently, and also used in the fields of medicine, health and commodity. The progress of total synthesis, structure modification and biological activities of azadirachtin is reviewed.

Key words: total synthesis, structure modification, bioactivity, azadirachtin