Catalytic Hydrolysis of Bis(p-nitrophenyl)phosphate Diester and Plasmid DNA by Dinuclear Macrocyclic Polyamine  La(III) Complexes Bearing Multiethoxyl Groups

Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (04): 580-583. Previous Articles Next Articles

Original Articles

多羟乙基双核大环多胺La(III)配合物对双对硝基苯酚磷酸二酯和DNA 催化水解作用研究

向清祥*; 张丽群; 余孝其; 谢如刚

(a乐山师范学院化学与生命科学学院乐山 614004)
(b四川大学化学学院成都 610064)

收稿日期:2008-09-19 修回日期:2008-10-20 发布日期:2009-04-20
通讯作者: 向清祥

Catalytic Hydrolysis of Bis(p-nitrophenyl)phosphate Diester and Plasmid DNA by Dinuclear Macrocyclic Polyamine La(III) Complexes Bearing Multiethoxyl Groups

Xiang, Qingxiang*; Zhang, Liqun; Yu, Xiaoqi ; Xie, Rugang

(a Department of Chemistry and Life Science, Leshan Teachers College, Leshan 614004)
(b Department of Chemistry, Sichuan University, Chengdu 610064)

Received:2008-09-19 Revised:2008-10-20 Published:2009-04-20
Contact: Xiang, Qingxiang

Abstract

A series of novel dinuclear macrocyclic polyamine La(III) complexes bearing multiethoxyl groups have been synthesized in this paper and their structures were characterized by 1H NMR, MS techniques and elemental analysis. The hydrolysis of bis(p-nitrophenyl)phosphate diester and the cleavage of plasmid DNA (pUC18) have been investigated by UV-visible spectrophotometric titration and the agarose gel electrophoresis. The results indicated that these La(III) complexes could effectively catalyze the hydrolysis of bis(p-nitrophenyl)phosphate diester and the cleavage of plasmid DNA (pUC18) under physiological conditions. The hydrolysis rate enhancement of bis(p-nitrophenyl)phosphate diester was up to 2.36×104 fold. The effects of the structure on the hydrolytic reactions were discussed.

Key words: dinuclear macrocyclic polyamine, complex, hydrolysis of bis(p-nitrophenyl)phosphate diester, DNA

Cite this article

Xiang, Qingxiang*; Zhang, Liqun; Yu, Xiaoqi ; Xie, Rugang

. Catalytic Hydrolysis of Bis(p-nitrophenyl)phosphate Diester and Plasmid DNA by Dinuclear Macrocyclic Polyamine La(III) Complexes Bearing Multiethoxyl Groups[J]. Chin. J. Org. Chem., 2009, 29(04): 580-583.

Export EndNote|Reference Manager|ProCite|BibTeX|RefWorks

[1]	Wenfang Wang. Recent Progress in Transition-Metal-Catalyzed Asymmetric C—H Borylation [J]. Chinese Journal of Organic Chemistry, 2023, 43(9): 3146-3166.
[2]	Changjun Liu, Huiling Hu, Chenghong Liu, Chaojie Zhu, Tiandi Tang. Pd Supported on Mesoporous ETS-10 Zeolite Catalyst with Superior Catalytic Performances in Synthesizing 1,2-Diones from the Oxidation of Internal Alkynes [J]. Chinese Journal of Organic Chemistry, 2023, 43(8): 2953-2960.
[3]	Suzhen Zhang, Wenwen Zhang, Hui Yang, Qing Gu, Shuli You. Rhodium-Catalyzed Enantioselective Spiroannulation of 2-Alkenylphenols with Alkynes [J]. Chinese Journal of Organic Chemistry, 2023, 43(8): 2926-2933.
[4]	Min Wu, Bo Liu, Jialong Yuan, Qiang Fu, Rui Wang, Dawei Lou, Fushun Liang. Recent Progress in the C—S Bond Formation Reactions Mediated by Visible Light [J]. Chinese Journal of Organic Chemistry, 2023, 43(7): 2269-2292.
[5]	Yue Zhu, Lu Chen, Jing Zhao, Qingrong Sun, Weiqing Yang, Haiyan Fu, Menglin Ma. Synthesis of Quinoline Derivatives by Friedländer Reaction Catalyzed by Ruthenium Complexes of Substituted 8-Hydroxyquinoline [J]. Chinese Journal of Organic Chemistry, 2023, 43(7): 2528-2542.
[6]	Liangru Yang, Mengli Guo, Jinwei Yuan, Jiamei Wangx, Yuting Xia, Yongmei Xiao, Pu Mao. Research Progress on Pincer N-Heterocyclic Carbene Metal Complexes [J]. Chinese Journal of Organic Chemistry, 2023, 43(6): 2002-2025.
[7]	Shuang Liu, Lianghua Zou, Xiaoming Wang. Advance of Dehydrogenation and Transfer Hydrogenation of Ammonia-Borane Catalyzed by Homogeneous Cobalt Complexes [J]. Chinese Journal of Organic Chemistry, 2023, 43(5): 1713-1725.
[8]	Yan Dang, Chaohong Jia, Yalan Wang, Li Wang, Yafei Li, Yahong Li. Synthesis and Characterization of Zinc, Lithium and Magnesium Complexes Containing Pyrrolyl Ligands, and Utilization as Catalysts in Borylation of Aryl Iodides and Hydroboration of Aldehydes and Ketones [J]. Chinese Journal of Organic Chemistry, 2023, 43(3): 1124-1135.
[9]	Xuqin Zhong, Zhen Liu. Conformational Screening of the Catalyst System Containing Transition Metal and Flexible Ligand [J]. Chinese Journal of Organic Chemistry, 2023, 43(2): 734-741.
[10]	Jun Liu, Jiajian Peng, Ying Bai, Jiayun Li, Zijie Song, Peng Liu, Ting Ouyang, Huilin Lan. Progress in Photocatalytic Hydrosilylation [J]. Chinese Journal of Organic Chemistry, 2023, 43(10): 3558-3568.
[11]	Biao Han, Yaoyao Zhang, Shuhan Chen, Mengge Zhao, Nan Li, Weishuang Li, Lei Zhu. Preparation of Axially Grafted Temperature-Responsive Chiral Salen Mn^III and Application in Asymmetric Epoxidation of Olefins in Water [J]. Chinese Journal of Organic Chemistry, 2023, 43(1): 244-253.
[12]	Xuefeng Jia, Xiangjuan Tong. Recent Progress on Chan-Lam Coupling Reactions Catalyzed by Copper(II) Complexes [J]. Chinese Journal of Organic Chemistry, 2022, 42(9): 2640-2658.
[13]	Mei Wang, Huihua Gong, Haiyan Fu, Xueli Zheng, Hua Chen, Ruixiang Li. Ruthenium Complex-Catalyzed Tandem Reactions of Alcohols with Acetonitriles for Synthesis of α-Substituted Amides [J]. Chinese Journal of Organic Chemistry, 2022, 42(8): 2418-2427.
[14]	Li Guan, Yongbao Mao, Yanyan Zhou, Xiaowen Feng, Yile Fu. Research Progress in Cyanine-Based Recognition Probes for G-Quadruplex DNA [J]. Chinese Journal of Organic Chemistry, 2022, 42(8): 2406-2417.
[15]	Jinsong Hou, Gaosheng Yang. Reaction of Tandem Addition of Aliphatic Amines to Alkenylnitriles Catalyzed by Tris(o-dimethylaminobenzyl)yttrium [J]. Chinese Journal of Organic Chemistry, 2022, 42(7): 2070-2078.

多羟乙基双核大环多胺La(III)配合物对双对硝基苯酚磷酸二酯和DNA 催化水解作用研究

Catalytic Hydrolysis of Bis(p-nitrophenyl)phosphate Diester and Plasmid DNA by Dinuclear Macrocyclic Polyamine La(III) Complexes Bearing Multiethoxyl Groups

PDF

Knowledge

Cited

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments