The compounds of possessing C_3- and G_4-units with additional functional groups are promising materials for the synthesis of various useful compounds. In particular, optically active C_3- and G_4- synthetic units are quite important intermediates for the preparation of pharmaceuticals and fine chemicals. Microbial transformation showing the enzyme stereospecificities has been applied to the asymmetric synthesis of optically active substance. In this review the recent works on the practical production of C_3- and G_4-synthetic units with microbial enzymes are described.

Key words: MICROBE, ENZYMATIC SYNTHESIS, STEREOSELECTIVITY