Chin. J. Org. Chem. ›› 1989, Vol. 9 ›› Issue (1): 83-88. Previous Articles     Next Articles

猪去氧胆酸的化学I: Δ^5-7-酮胆烷酸甲酯系列的还原研究

王锺麒;阙浩泉;姜立中;周维善   

  1. 中国科学院上海有机化学研究所
  • 发布日期:1989-02-25

Chemistry of hyodeoxycholic acid I: Study on reduction of methyl-Δ^5-7-ketocholanate series

WANG ZHONGQI;QUE HAOQUAN;JIANG LIZHONG;ZHOU WEISHAN   

  • Published:1989-02-25

Me D5-ketocholanate I, obtained from hyodeoxycholic acid, was hydrogenated over 5% Pd/CaCO3 or Pd(OH)2 in the neutral, alkaline or acidic medium. Thus, ketocholanate II was obtained in 98% yields by catalytic hydrogenation in Me2CHOH.

Key words: CHOLANES, REDUCTION, STEROIDS, BILE ACID, HYODEOXYCHOLIC ACID

CLC Number: