Chin. J. Org. Chem. ›› 1990, Vol. 10 ›› Issue (2): 159-162. Previous Articles     Next Articles

Original Articles

甲基吡啶侧链金属化和烷基化反应的研究

邹多秀;曾宪谋;马兆兰;顾以健;张秀峰;咸桂莲;郭春香   

  1. 中国科学院大连化学物理研究所
  • 发布日期:1990-04-25

Studies on reactions of lateral metallation and alkylation of picolines

ZHOU DUOXIU;ZENG XIANMOU;MA ZHAOLAN;GU YIJIAN;ZHANG XIUFENG;XIAN GUILIAN;GUO CHUNXIANG   

  • Published:1990-04-25

Picoline can be metalated by picoline radical anion sodium complex (CH3C5H4N-Na+) and the resulting picolysodium intermediate underwent alkylation subsequently with alkyl halide. It is a convenient method for synthesizing longer chain a-and g-alkyl pyridines from a-and g-picoline, resp.

Key words: PYRIDINE P, PYRIDINE P, REACTION MECHANISM, HALOHYDROCARBON, METALATION, ALKYLATION, SODIUM, SIDE CHAIN, LONG CHAIN COMPOUND

CLC Number: