Microwave-Assisted Desulfurization of Significant Biologically Active Compounds by Raney Nickel

Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (01): 60-64. Previous Articles Next Articles

Original Articles

Raney镍催化下生物活性化合物的微波辅助脱硫反应

PANUNZIO, Mauro*^,a，BANDINI, Elisa^b，D'AURIZIO, Anto-nio^b
MARTELLI, Giorgio^b，TAMANINI, Emiliano^b
肖尚友^c，夏之宁*^,c

(^a ISOF-CNR Dipartimento di Chimica “G. Ciamician” Via Selmi, 240126 Bologna, Italy)
(^bISOF-CNR Via Gobetti 101, 40121 Bologna, Italy)
(^c重庆大学化学化工学院药学系重庆 400044)

收稿日期:2006-11-01 修回日期:1900-01-01 发布日期:2008-01-23
通讯作者: 夏之宁

Microwave-Assisted Desulfurization of Significant Biologically Active Compounds by Raney Nickel

PANUNZIO Mauro*^,a, BANDINI Elisa^b, D'AURIZIO An-tonio^b, MARTELLI Giorgio^b TAMANINI Emili-ano^b, XIAO Shang-You^c, XIA Zhi-Ning*^,c

(^aISOF-CNR Dipartimento di Chimica “G. Ciamician” Via Selmi, 240126 Bologna, Italy)

Received:2006-11-01 Revised:1900-01-01 Published:2008-01-23
Contact: XIA Zhi-Ning

Abstract

Microwave-assisted desulfurization reaction, which has the advantages of fast speed and high yields, has become one of the most efficient desulfurization methods. It will be used more and more extensively in the synthesis of biologically active compounds. In this paper, a series of significant biologically active molecules were prepared by microwave-assisted reduction of the corresponding phenylthio substituted precursors by Raney nickel using ethanol as solvent.

Key words: desulfurization, heterocyclic compound, microwave-assisted organic synthesis, gabapentin, β-lactam

Cite this article

PANUNZIO Mauro*^,a, BANDINI Elisa^b, D'AURIZIO An-tonio^b, MARTELLI Giorgio^b TAMANINI Emili-ano^b, XIAO Shang-You^c, XIA Zhi-Ning*^,c. Microwave-Assisted Desulfurization of Significant Biologically Active Compounds by Raney Nickel[J]. Chin. J. Org. Chem., 2008, 28(01): 60-64.

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Raney镍催化下生物活性化合物的微波辅助脱硫反应

Microwave-Assisted Desulfurization of Significant Biologically Active Compounds by Raney Nickel

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