Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (03): 506-510. Previous Articles     Next Articles

Reports

新型含吡唑基的查尔酮的合成、表征及晶体结构

解正峰a,貊雪霞a,刘方明*,a,b   

  1. (a新疆大学石油天然气精细化工教育部重点实验室 乌鲁木齐 830046)
    (b杭州师范大学材料与化学化工学院 杭州 310012)
  • 收稿日期:2007-04-25 修回日期:2007-07-12 发布日期:2008-03-18
  • 通讯作者: 刘方明

Synthesis, Characterization and Single Crystal Structures of Pyrazol-4-yl-contaning Chalcone Compounds

XIE Zheng-Fenga,MO Xue-Xiaa,LIU Fang-Ming*,a,b   

  1. (a Key Laboratory of Oil & Gas Fine Chemicals, Ministry of Education, Xinjiang University, Urumqi 830046)
    (b College of Material, Chemistry and Chemical En-gineering, Hangzhou Normal University, Hangzhou 310012)
  • Received:2007-04-25 Revised:2007-07-12 Published:2008-03-18
  • Contact: LIU Fang-Ming

Ten chalcones were synthesized by aldol condensation reaction of acetophenone or para-substituted acetophenones with 1-phenyl-3-methyl-5-phenoxylpyrazole-4-aldehyde in the strong alkali condition. The structures were characterized by elemental analysis, IR, 1H NMR spectra, and the structure of 4c was confirmed by X-ray single-crystal diffraction analysis. The crystal of the compound 4c belongs to triclinic, space group P-1 with cell parameters a=1.0225(2) nm, b=1.4263(3) nm, c=1.6718(3) nm, α=110.32(3)°, β=106.30(3)°, γ=98.11(3)°, Mr=428.90, V=2.1159(7) nm3, Dc=1.346 Mg/m3, Z=2, and F(000)=896.

Key words: pyrazole, characterization, chalcone, crystal structure