The synthesis of thiocarbohydrazones and thiosemicarbazones containing ferrocenyl group

Abstract

Some new thiosemicarbazones and thiocarbohydrazones containing ferrocenyl group R1CMe:NNHC(S)NHR2[R1 = h5-C5H5FeC5H4, h5-C5H5FeC5H4COCH2, R2 = Ph, 2-naphthyl], R3CMe:NNHC(S)NHNH2, R3CMe:NNHC(S)NHN:CR4R5 [R3 = h5-C5H5FeC5H4; R4 = Me, R5 = h5-C5H5FeC5H4; R4 = H, R5 = 2-C6H4OH; R4 = Me, R5 = 2-hydroxy-4-methylphenyl] have been synthesized by the condensation of appropriate derivatives of ferrocene and thiocarbohydrazide or thiosemicarbazide in EtOH in the presence of AcOH. All compounds have not been reported so far and their structures have been confirmed by elemental anal., 1H NMR and IR. The reaction conditions for the synthesis of these compounds are also discussed.

Key words: ACETIC ACID, ETHANOL, FERROCENE P, CONDENSATION, THIOSEMICARBAZONE

CLC Number:

O621

Cite this article

HUANG GUOSHENG;LIANG YONGMIN;WU LIZHU;MA YONGXIANG. The synthesis of thiocarbohydrazones and thiosemicarbazones containing ferrocenyl group[J]. Chin. J. Org. Chem., 1992, 12(4): 408-411.

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