The possibility of 1,4-asymmetric induction in some nucleophilic addition reactions of chiralγ-amino Z-enals 7 with organolithium compounds was investigated. The reactions of lithium enolates with 7 led to good diastereoselectivities (d.e.: 60～90%), and high level of diadtereoselectiveties (d.e.: 74～86%) was also observed in the corresponding reactions of alkyllithium. This means that a novel remote 1,4-asymmetric induction results in these reactions.

Key words: CONJUGATED DOUBLE BOND COMPOUNDS, STEREOSELECTIVITY, OLEFINE ALDEHYDE, ORGANO LITHIUM COMPOUNDS, ASYMMETRY INDUCTION, CIS-FORM COMPOUNDS