Chin. J. Org. Chem. ›› 2000, Vol. 20 ›› Issue (6): 900-904. Previous Articles     Next Articles

α-三唑基查尔酮与苯肼的加成-关环反应研究

刘天麟;谢建华;杨卓鸿   

  1. 南开大学元素有机化学研究所.天津(300071)
  • 发布日期:2000-12-25

Study on the addition-cyclization of α-triazolyl chalcone and phenylhydrazine

Liu Tianlin;Xie Jianhua;Yang Zhaohong   

  1. Nankai Univ, Elementoorgan Chem Lab.Tianjin(300071)
  • Published:2000-12-25

The reaction of (Z)&(E)-1,3-diaryl-2-(1H-1,2,4-triazo-1-lyl)-2- propen-1-one and phenylhydrazine in acetic acid medium afforded a mixture of cis and trans 1,3,5-triphenyl-4-triazolyl-2-pyrazoline. In triethylamine, only trans isomer was obtained. Three pairs of cis and trans 1,3,5-triphenyl-4-triazolyl-2-pyrazoline (1a~1c and 2a~2c) were obtained altogether. A reaction machanism via 1,4-addition followed cyclization is postulated.

Key words: PYRRODIAZOLE P, CHALCONE, PHENYLHYDRAZINE, ADDITION REACTION, CYCLIZATION, REACTION MECHANISM, PROTON MAGNETIC RESONANCE SPECTROMETRY

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