Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (06): 745-756.     Next Articles

Review

N-杂环卡宾: 一种多用途有机小分子催化剂

孙小宇1,吴劼*,1,2   

  1. (1复旦大学化学系 上海 200433)
    (2中国科学院上海有机化学研究所金属有机化学国家重点实验室 上海 200032)
  • 收稿日期:2005-06-18 修回日期:2005-10-28 发布日期:2006-05-31
  • 通讯作者: 吴劼

N-Heterocyclic Carbene: a Versatile Organocatalyst

SUN, Xiao-Yua1,WU, Jie*,1,2   

  1. (1Department of Chemistry, Fudan University, Shanghai 200433))
    (2(b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032)
  • Received:2005-06-18 Revised:2005-10-28 Published:2006-05-31
  • Contact: WU, Jie

In recent years N-heterocyclic carbenes (NHC) have evoked considerable interest, and this can be attributed in large measure to the isolation of a stable imidazol-2-ylidene by Arduengo et al. in 1991. Although the use of NHC as ligands in organometallic reactions has been studied extensively, the study of N-heterocyclic carbenes used as the reaction reagents and catalysts still need to be conducted deeply. The purpose of this passage is to cast some light on the chemistry of NHC as organocatalysts and to inspire organic chemists to pay more attention to this hot field.

Key words: stetter reaction, umpolung reaction, organocatalyst, N-heterocyclic carbene