Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (08): 1326-1335. Previous Articles     Next Articles

Review

树枝状化合物作为药物载体的研究进展

何 谷 ; 郭 丽*   

  1. (四川大学华西药学院药物化学系 靶向药物教育部重点实验室 成都 610041)
  • 收稿日期:2007-05-09 修回日期:2007-10-08 发布日期:2008-08-18
  • 通讯作者: 郭 丽

Progress in Dendrimers as Drug Carriers

HE, Gu ; GUO, Li*   

  1. (Key Laboratory of Drug Targeting of Ministry of Education, Department of Medicinal Chemistry,
    West China School of Pharmacy, Sichuan University, Chengdu 610041)
  • Received:2007-05-09 Revised:2007-10-08 Published:2008-08-18
  • Contact: GUO, Li

Dendrimers are monodisperse macromolecules with strict structures, which have a lot of unique physical and chemical characteristics different from normal polymers and widely applicated to the material, catalyst and biomedical areas. Dendrimers as drug carriers and their applications to the areas of antiviral, anti-tumor, peptide and saccharide analogues are discussed.

Key words: dendrimer, antiviral, anti-tumor, peptide analogue, drug carrier