Rapid and Highly Efficient Microwave-Assisted C—N, C—O and C— S Coupling Reactions without a Transition-Metal Catalyst

doi:10.6023/cjoc1108302

Chin. J. Org. Chem. ›› 2012, Vol. 32 ›› Issue (04): 732-741.DOI: 10.6023/cjoc1108302 Previous Articles Next Articles

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无催化剂微波促进下C—O, C—N 和C—S 交叉偶联反应研究

袁艳琴, 郭圣荣, 莫建军, 钱利, 石泽凤

丽水学院化学化工系丽水 323000

收稿日期:2011-08-30 修回日期:2011-11-03 发布日期:2012-04-24
通讯作者: 郭圣荣 E-mail:guosr9609@lsu.edu.cn
基金资助:
浙江省自然科学基金基金(No. Y407240)和丽水学院重点科研(No. KZ20H03)资助项目.

Rapid and Highly Efficient Microwave-Assisted C—N, C—O and C— S Coupling Reactions without a Transition-Metal Catalyst

Yuan Yanqin, Guo Shengrong, Mo Jianjun, Qian Li, Shi Zefeng

Department of Chemistry, Lishui University, Lishui 323000

Received:2011-08-30 Revised:2011-11-03 Published:2012-04-24
Supported by:
Project supported by the Natural Science Foundation of Zhejiang Province (No. Y407240) and the Key Science Foundation of Lishui University (No. KZ20H03).

A rapid and direct coupling reactions of various N/O/S nucleophilic reagents with aryl halides have been developed in good to high yields under microwave irradiation without a transition-metal catalyst. These reactions are a particularly powerful method for the coupling of electron-withdraw aryl halides with various nucleophilic reagents. A variety of products including aryl ethers, N-arylamides, and aryl thioethers were synthesized in good to excellent yields.

Key words: microwave, cross-coupling reactions, aryl ethers, aryl thioethers, N-arylation

Cite this article

Yuan Yanqin, Guo Shengrong, Mo Jianjun, Qian Li, Shi Zefeng. Rapid and Highly Efficient Microwave-Assisted C—N, C—O and C— S Coupling Reactions without a Transition-Metal Catalyst[J]. Chin. J. Org. Chem., 2012, 32(04): 732-741.

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无催化剂微波促进下C—O, C—N 和C—S 交叉偶联反应研究

Rapid and Highly Efficient Microwave-Assisted C—N, C—O and C— S Coupling Reactions without a Transition-Metal Catalyst

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