Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (12): 2618-2621.DOI: 10.6023/cjoc201306031 Previous Articles     Next Articles

Notes

炭角菌Xylaria sp. 290代谢产物中两个新的海松烷型二萜

徐培培a, 尤怀成b, 胡志钰b, 李瑶瑶c, 沈月毛a,c   

  1. a 山东大学生命科学学院 济南 250100;
    b 厦门大学生命科学学院 厦门 361005;
    c 山东大学药学院 济南 250012
  • 收稿日期:2013-06-20 修回日期:2013-07-09 发布日期:2013-08-13
  • 通讯作者: 沈月毛 E-mail:yshen@sdu.edu.cn
  • 基金资助:

    国家重点基础研究发展计划(973计划,No. 2010CB833802)资助项目.

Two New Pimarane-Type Diterpenes from the Metabolites of Xylaria sp. 290

Xu Peipeia, You Huaichengb, Hu Zhiyub, Li Yaoyaoc, Shen Yuemaoa,c   

  1. a School of Life Sciences, Shandong University, Jinan 250100;
    b School of Life Sciences, Xiamen University, Xiamen 361005;
    c School of Pharmaceutical Sciences, Shandong University, Jinan 250012
  • Received:2013-06-20 Revised:2013-07-09 Published:2013-08-13
  • Supported by:

    Project supported by the Major State Basic Research Development Program of China (973 Program, No. 2010CB833802).

Two new pimarane-type diterpenes, xylarianes A (1) and B (2), were isolated from the crude extract of the fungus Xylaria sp. 290 along with one known compound of 16-hydroxy-isopimar-7-en-19-oic acid (3). The chemical structures of 13 were elucidated by spectroscopic methods including 1D-NMR and 2D-NMR experiments and HR-ESIMS. The antitumor assay of compounds 13 showed that they have no activities.

Key words: pimarane, diterpene, Xylaria sp.