Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (12): 2612-2617.DOI: 10.6023/cjoc201306028 Previous Articles     Next Articles

Notes

新型含1,3,4-噻二唑的硫脲化合物的合成及除草活性

孙召慧, 黄伟, 贡云芸, 蓝健, 刘幸海, 翁建全, 李永曙, 谭成侠   

  1. 浙江工业大学化学工程与材料学院 杭州 310014
  • 收稿日期:2013-06-19 修回日期:2013-07-19 发布日期:2013-08-13
  • 通讯作者: 谭成侠 E-mail:tanchengxia@zjut.edu.cn
  • 基金资助:

    “十二五”国家科技攻关计划(No. 2011BAE06B03-01)和浙江省重点科技创新团队(No. 2010R50018)资助项目.

Synthesis and Herbicidal Activity of New 1,3,4-Thiadizols Sulfourea Derivative

Sun Zhaohui, Huang Wei, Gong Yunyun, Lan Jian, Liu Xinghai, Weng Jianquan, Li Yongshu, Tan Chengxia   

  1. College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310014
  • Received:2013-06-19 Revised:2013-07-19 Published:2013-08-13
  • Supported by:

    Project supported by the National Key Technologies R & D Program (No. 2011BAE06B03-01) and the Key Innovation Team of Science and Technology in Zhejiang Province (No. 2010R50018).

To find new pesticidal lead compounds with high bioactivity, 18 acylthioureas contain 1,3,4-thiadizols were obtained by condensation between acyl isothiocyanate and 1,3,4-thiadiazols. Their structures were confirmed by 1H NMR and MS. The herbicidal activities of these compounds were evaluated. All the compounds have herbicidal activity at 200 g ai/ha. The bioassay results showed that compound 5b had 90% inhibitory effect against Echinochloa crusgalli, Setaira viridis, Digitaria sanguinalis, Amaranthus retroflexus and Eclipta prostrate at 200 g ai/ha in pre-emergence condition and 90% and 95% against Echinochloa crusgalli and Eclipta prostrate at 200 g ai/ha in post-emergence condition, respectively; and compound 5e had 100% inhibitory effect against Echinochloa crusgalli, Setaira viridis, Digitaria sanguinalis and Amaranthus retroflexus at 200 g ai/ha in post-emergence and post-emergence condition.

Key words: acyl thiourea, 1,3,4-thiadiazol, synthesis, herbicidal activity