Recent Development of Indole Synthesis by Transition Metal Catalyzed C—H Functionalization

doi:10.6023/cjoc201505031

Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (11): 2275-2290.DOI: 10.6023/cjoc201505031 Previous Articles Next Articles

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过渡金属催化的C—H键官能团化构建吲哚结构的研究进展

卢贝丽, 李现艳, 林咏梅

福建农林大学材料工程学院福州 350002

收稿日期:2015-05-19 修回日期:2015-06-29 发布日期:2015-07-10
通讯作者: 卢贝丽 E-mail:lubl@fafu.edu.cn
基金资助:
国家自然科学基金(Nos. 21402027)、福建省自然科学基金(No. 2015J05046)、福建省教育厅A类科技(No. JA14108)资助项目.

Recent Development of Indole Synthesis by Transition Metal Catalyzed C—H Functionalization

Lu Beili, Li Xianyan, Lin Yongmei

College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350002

Received:2015-05-19 Revised:2015-06-29 Published:2015-07-10
Supported by:
Project supported by the National Natural Science Foundation of China (No. 21402027), the Natural Science Foundation of Fujian Province (No. 2015J05046) and the Education Department of Fujian Province (No. JA14108).

Indoles represent important scaffolds in a large family of bioactive molecules and natural products. These compounds display a wide range of unique properties, which have been widely applied to clinical pharmaceuticals, materials and industries. In recent years, transition metal catalyzed C—H bond functionalization for the efficient construction of indole motifs has attracted much attention from chemical society. This review presents the recent development in this area and highlights the different advantages associated with transition metal catalyzed C—H bond functionalizations. The applications of the methodology on the synthesis of natural products and bioactive molecules containing indole skeletons have also been introduced.

Key words: indole, transition metal catalysis, C—H functionalization

Cite this article

Lu Beili, Li Xianyan, Lin Yongmei. Recent Development of Indole Synthesis by Transition Metal Catalyzed C—H Functionalization[J]. Chin. J. Org. Chem., 2015, 35(11): 2275-2290.

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过渡金属催化的C—H键官能团化构建吲哚结构的研究进展

Recent Development of Indole Synthesis by Transition Metal Catalyzed C—H Functionalization

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