Synthesis of Heterocyclic Aromatic Sulfides under Microwave Irradiation

doi:10.6023/cjoc201509026

Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (2): 352-357.DOI: 10.6023/cjoc201509026 Previous Articles Next Articles

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微波促进下含苯并杂环芳硫醚的合成

张变香, 杨丽花, 史瑞雪, 亢永强

山西大学化学化工学院太原 030006

收稿日期:2015-09-21 修回日期:2015-10-14 发布日期:2015-10-26
通讯作者: 张变香 E-mail:zbxthh@sxu.edu.cn
基金资助:
山西省科技创新项目(No. 2014101011)及山西大学本科生科研训练(No. 2014013)资助项目

Synthesis of Heterocyclic Aromatic Sulfides under Microwave Irradiation

Zhang Bianxiang, Yang Lihua, Shi Ruixue, Kang Yongqiang

School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006

Received:2015-09-21 Revised:2015-10-14 Published:2015-10-26
Supported by:
Project supported by the Science and Technology Innovation Project of Shanxi Province (No. 2014101011) and the Undergraduate Research Training Program of Shanxi University (No. 2014013).

1. Synthesis of Heterocyclic Aromatic Sulfides under Microwave Irradiation.PDF(998KB)

Abstract

The reaction of the thiolazole compounds with aryl iodide resulted in a series of aryl thioether compounds under microwave irradiation. It showed that the yield of target product was 88% when the reaction was carried out under microwave (30 W) heating for 15 min in N,N-dimethylformamide (DMF). The target products using microwave response and oil bath heating were tracked separately by high performance liquid chromatography (HPLC) analysis under the same conditions. The results showed that the method of microwave irradiation for the preparation of aryl sulfide was simple, efficient, time-saving and less by-products. It is expected to become an efficient, gentle and environmentally friendly synthetic method of heterocyclic aryl sulfides.

Key words: 2-mercaptobenzo heterocyclic, aryl iodide, aryl thioether, microwave irradiation, high performance liquid chromatography (HPLC)

Cite this article

Zhang Bianxiang, Yang Lihua, Shi Ruixue, Kang Yongqiang. Synthesis of Heterocyclic Aromatic Sulfides under Microwave Irradiation[J]. Chin. J. Org. Chem., 2016, 36(2): 352-357.

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微波促进下含苯并杂环芳硫醚的合成

Synthesis of Heterocyclic Aromatic Sulfides under Microwave Irradiation

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