Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (4): 883-902.DOI: 10.6023/cjoc201808039 Previous Articles     Next Articles

Special Issue: 碳氢活化合辑2018-2019



王辉, 黄龙江   

  1. 青岛科技大学化工学院 青岛 266042
  • 收稿日期:2018-08-30 修回日期:2018-11-14 发布日期:2018-12-05
  • 通讯作者: 黄龙江
  • 基金资助:


Progress in Imine Formation from Direct Coupling of Alcohols and Amines Catalyzed by Metal Catalysts

Wang Hui, Huang Longjiang   

  1. College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042
  • Received:2018-08-30 Revised:2018-11-14 Published:2018-12-05
  • Contact: 10.6023/cjoc201808039
  • Supported by:

    Project supported by the Higher Educational Science and Technology Program of Shandong Province (No. J16LC13).

Imines are very important class of compounds and have been widely utilized in fine chemicals, pharmaceuticals and chemical industry. The C=N double bond in imine is an important nitrogen source in different types of reactions due to its high reactive activity. Due to its high atom economy, catalytic direct coupling of alcohols and amines to imines based on metal catalysts has attracted much attention and maken great progress in recent years. In this paper, the advances in direct coupling of alcohols and amines to imines catalyzed by metal catalysts are reviewed.

Key words: imine, alocohols, amines, metal catalysis