Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (1): 1-11.DOI: 10.6023/cjoc202008037 Previous Articles Next Articles
Special Issue: 热点论文虚拟合集
ACCOUNT
郑雨a, 谢珍珍a, 陈凯a, 向皞月a,*(), 阳华a,*()
收稿日期:
2020-08-20
修回日期:
2020-09-22
发布日期:
2020-10-12
通讯作者:
向皞月, 阳华
作者简介:
郑雨, 2012~2016年就读于中南大学化学化工学院, 获得学士学位; 2016~2019年就读于中南大学化学化工学院, 获得硕士学位; 2019年至今在中南大学化学化工学院阳华课题组攻读博士学位. 主要研究方向为有机小分子催化及新型有机小分子催化剂的设计、合成与应用. |
谢珍珍, 2014~2018年就读于吉首大学化学化工学院, 获得学士学位; 2018年至今在中南大学化学化工学院阳华教授课题组攻读硕士学位. 主要研究方向为有机催化合成含氮含氧杂环. |
陈凯, 博士, 讲师. 2005~2009年就读于南开大学药学院, 获得学士学位. 2009~2014年就读于北京大学化学化工学院, 获得理学博士学位, 师从吴云东教授和Olaf Wiest教授, 在表观遗传学调控蛋白与小分子的相互作用机制以及抑制剂设计方面取得了一定进展, 对组蛋白去乙酰化酶家族的选择性抑制提出了新的理论模型. 2015年加入华南理工大学化学化工学院祝诗发课题组从事博士后工作, 对过渡金属催化的烯炔醛环异构化反应机理进行了深入的理论研究. 2019年在韩国高等科学技术院Mookie Baik课题组进行访问研究. 2019年年底加入中南大学化学化工学院, 主要从事基于自由基中间体串联反应的机理研究以及新型有机催化剂的设计开发. |
向皞月, 博士, 副教授, 硕士生导师. 2006~2010年就读于湖南师范大学化学化工学院, 获得学士学位. 2010~2015就读于中国科学院上海药物研究所, 获得博士学位, 在杂环化合物库的构建、苗子/先导化合物的发现取得了一定进展. 构建了基于色酮的含氮杂环小分子化合物库, 并从中发现了一些结构新颖的抗肿瘤先导化合物, 设计合成了系PI3K抑制剂, 在体外表现出良好的抗肿瘤活性. 2015年至今于中南大学化学化工学院承担有机化学、药物化学等教学工作, 并开展研究工作. 致力于光氧化还原催化体系研究以及含氮/氟杂环小分子化合物库构建新方法的开发. |
阳华, 博士, 中南大学海外高层次人才“升华学者”特聘教授, 博士生导师. 1991~1995年就读于四川大学精细化工专业, 获得学士学位; 1996~1998年就读于四川大学有机化学专业, 获得硕士学位; 2001~2006就读于美国西弗吉尼亚大学, 获得博士学位; 2006~2011年在美国俄勒冈州立大学开展博士后研究工作, 并随后被提升为助理研究员独立开展研究工作; 2011年至今以中南大学“升华学者”特聘教授进入中南大学化学化工学院任教并开展研究工作. 主要从事有机合成和催化方面的研究, 重点在手性催化、光催化、复杂手性药物分子的合成与改性等领域取得了系列研究成果. |
基金资助:
Yu Zhenga, Zhenzhen Xiea, Kai Chen,a, Haoyue Xiang,a,*(), Hua Yang,a,*()
Received:
2020-08-20
Revised:
2020-09-22
Published:
2020-10-12
Contact:
Haoyue Xiang,, Hua Yang,
Supported by:
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Yu Zheng, Zhenzhen Xie, Kai Chen,, Haoyue Xiang,, Hua Yang,. Application of Organocatalysis in Asymmetric Construction of Nitrogen-Containing Heterocyclic Compounds[J]. Chinese Journal of Organic Chemistry, 2021, 41(1): 1-11.
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