Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (1): 12-51.DOI: 10.6023/cjoc202007045 Previous Articles     Next Articles

Special Issue: 热点论文虚拟合集

REVIEWS

通过环加成反应和串联反应构建桥环化合物的研究进展

王乐乐a, 张子莹a, 韩华彬a, 刘雄利b, 卜站伟a, 王琪琳a,*()   

  1. a 河南大学化学化工学院 河南开封 475004
    b 贵州大学贵州药食植物资源研究开发中心 贵阳 550025
  • 收稿日期:2020-07-18 修回日期:2020-08-29 发布日期:2020-09-16
  • 通讯作者: 王琪琳
  • 作者简介:
    * Corresponding author. E-mail:
  • 基金资助:
    国家自然科学基金(U1504206); 中国博士后科学基金(2020M672200); 河南大学(SYL19060137); 河南大学(SYL19030204)

Recent Advances in the Construction of Bridged Rings through Cycloadditions and Cascade Reactions

Lele Wanga, Ziying Zhanga, Huabin Hana, Xiongli Liub, Zhanwei Bua, Qilin Wanga,*()   

  1. a College of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475004
    b Guizhou Medicine Edible Plant Resources Research and Development Center, Guizhou University, Guiyang 550025
  • Received:2020-07-18 Revised:2020-08-29 Published:2020-09-16
  • Contact: Qilin Wang
  • Supported by:
    the National Natural Science Foundation of China(U1504206); the China Postdoctoral Science Foundation(2020M672200); the Henan University(SYL19060137); the Henan University(SYL19030204)

Bridged rings are frequently encountered in natural products and biologically active molecules, which have significant application in the field of medicinal chemistry, natural product chemistry, synthetic chemistry, material chemistry and life science. In recent years, with the unremitting efforts of a large number of chemists, a series of new methods have been developed for the efficient synthesis of bridged compounds. The detailed synthetic methods to access bridged compounds in the past five years involving cycloadditions and cascade reactions are summarized, and the advantages and problems of the current methods are briefly analyzed, which would provide useful reference for the researchers engaged in organic synthesis and related fields.

Key words: Keywords bridged ring, cycloaddition, cascade reaction