Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (12): 4015-4030.DOI: 10.6023/cjoc202008042 Previous Articles     Next Articles

N-取代-1,2,3-三氮唑化合物的合成研究进展

刘启顺a, 吕玉芬a, 鲍鹏丽a, 岳会兰b, 魏伟a,b   

  1. a 曲阜师范大学化学与化工学院 山东曲阜 273165;
    b 中国科学院西北高原生物研究所 中国科学院藏药研究重点实验室 西宁 810008
  • 收稿日期:2020-08-24 修回日期:2020-09-28 发布日期:2020-10-15
  • 通讯作者: 鲍鹏丽, 岳会兰, 魏伟 E-mail:weiweiqfnu@163.com;hlyue@nwipb.cas.cn;baopengli1992@163.com
  • 基金资助:
    山东省高校青创科技计划(No.2019KJC021)、国家自然科学基金(No.ZR2018MB009)、青海省国际合作专项(No.2018-HZ-806)资助项目.

Recent Progress in the Synthesis of N-Substituted-1,2,3-triazoles

Liu Qishuna, Lü Yufena, Bao Penglia, Yue Huilanb, Wei Weia,b   

  1. a School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, Shandong 273165;
    b Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008
  • Received:2020-08-24 Revised:2020-09-28 Published:2020-10-15
  • Supported by:
    Project supported by the Youth Innovation and Technology Project of Shandong Province (No. 2019KJC021), the Natural Science Foundation of Shandong Province (No. ZR2018MB009) and the International Cooperation Project of Qinghai Province (No. 2018-HZ-806).

N-Substituted-1,2,3-triazoles are an important class of nitrogen-containing hetrocyclic compounds, which exhibited wide applications in various fields such as medicinal chemistry, synthetic chemistry and materials. Therefore, their synthetic methods have attracted great attention of chemists. Herein, the recent research progress in the synthesis of N-substituted-1,2,3-triazoles is summarized. The synthetic routes and reaction mechanisms from raw materials such as azide compounds, diazo compounds, TsNHNH2, hydrazones and NH-1,2,3-triazoles are introduced and reviewed, respectively. Finally, the future development of this field is also prospected.

Key words: N-substituted-1,2,3-triazole, azide compound, hydrazone, TsNHNH2, diazo compound, NH-1,2,3-triazole