Progress in Synthesis of Pumiliotoxin Alkaloids

Chinese Journal of Organic Chemistry ›› 2004, Vol. 24 ›› Issue (10): 1151-1158. Previous Articles Next Articles

Pumiliotoxin类生物碱的合成研究新进展

唐本灿, 李卫东^*

兰州大学功能有机分子化学国家重点实验室兰州 730000

收稿日期:2003-09-03 修回日期:2003-12-02 接受日期:2004-03-05 发布日期:2022-09-20

Progress in Synthesis of Pumiliotoxin Alkaloids

TANG Ben-Can, LI Wei-Dong^*

State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000

Received:2003-09-03 Revised:2003-12-02 Accepted:2004-03-05 Published:2022-09-20
Contact: * E-mail: liwd@lzu.edu.cn, isoc@lzu.edu.cn;Fax: 0931-8912539.

Abstract

Pumiliotoxins and allopumiliotoxins,natural alkaloids separated from Dendrobate poison frogs, such as Dendrobates pumili, have attracted more and more interest of organic chemists. This article summarizes the syntheses of pumiliotoxin and allopumiliotoxin alkaloids,especially the total syntheses of pumiliotoxin 251D, in terms of the core skeleton construction.

Key words: pumiliotoxin, allopumiliotoxin, pumiliotoxin 251D, alkaloid, total synthesis

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TANG Ben-Can, LI Wei-Dong. Progress in Synthesis of Pumiliotoxin Alkaloids[J]. Chinese Journal of Organic Chemistry, 2004, 24(10): 1151-1158.

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(唐本灿, 硕士学位论文, 兰州大学, 兰州, 2003.)

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Pumiliotoxin类生物碱的合成研究新进展

Progress in Synthesis of Pumiliotoxin Alkaloids

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