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About the Cover:The recent advances in the asymmetric catalytic synthesis of α,β-unsaturated γ-lactones and γ-lactams are summarized by Shen, Wang, Wu, Xu and Zhang on page 2637, covering transition-metal catalysis, Lewis acid catalysis, and organocatalysis. The relevant discussions highlight stereocontrol mechanisms in representative examples and their potential applications. -
About the Cover:A visible-light-mediated [3+2] cycloaddition reaction between aryl alkynes and N-imine(iso)quinolinium ylides, catalyzed by the bisphosphonium salt Binap- (OTf)2, was developed by Miao, Zhang, Chen, Wang, and Duan on page 2876. This method delivers diverse pyrazo-lo[1,5-a]/[5,1-a](iso)quinoline derivatives, overcomes substrate limitations in the synthesis of β-aryl- substituted pyrazolo(iso)quinolines, and provides a mild, scalable route to nitrogen-fused heterocycles.
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