Chinese Journal of Organic Chemistry 2025, 45(7)

- About the Cover:
  
  Multi-substituted benzothiophene skeleton is an impor- tant synthetic intermediate. A practical method for the synthesis of such compounds via the insertion reaction of diazo compounds catalyzed by transition metals is provided by Cui, Jin, Huang, Qin and Ji on page 2501. This method features mild conditions and practical effi-ciency. Biological activity of several products was tested against cell lines including NIH-3T3, B16-F10, 4T1, and HCT116.
- About the Cover:
  
  The molecular design and applications of cyclometalated iridium(III) complexes [Ir(C^N)?(N^N)]? are summarized by Shi, Li and Li on page 2389. It focuses on strategies to improve visible light absorption and excited-state lifetimes, along with applications in photocatalytic synthesis and TTA-UC, highlighting correlations between structure and photosensitivity. This summary provides insights for developing high-performance iridium complexes.
- About the Cover:
  
  Chronic obstructive pulmonary disease (COPD) has garnered increased attention as a result of its persistent symptoms, which undermine patients? quality of life. Fudosteine has substantial advantages in the treatment of COPD due to its high efficacy and low adverse effects. Fudosteine sulfonamide derivatives Series I and amine derivatives Series II were designed and synthesized, and their biological activities were evaluated by Sun, Gui, Cheng, Yang and Li on page 2566.
- About the Cover:
  
  A novel Cs2CO3-promoted hydrocyanide reaction of the directing group-protected N-(quinolin-8-yl)but-3-enami- des with trimethylsilyl cyanide to afford 3-cyanobutyl- amides is described by Zhu, Cui and Zeng on page 2529. Mechanistic studies have shown that this reaction is a nucleophilic addition reaction of double bonds rather than a free radical reaction. The reaction has good chemoselectivity, and the substrate has a wide range of applicability.
2025, 45(7)

25 July 2025
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REVIEWS ARTICLES HIGHLIGHTS

REVIEWS

Research Progress on the Synthetic Applications of Direct Construction of Sulfonyl Fluoride Functional Groups Using "SO₂F" Sources

Zhe Han, Yin Cui, Chengrong Ding, Jian Yang, Guofu Zhang

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2245-2264 DOI: 10.6023/cjoc202409035

Abstract( 278) HTML( 8) PDF(1280KB)( 297 )

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Advances in Perylene Diimide-Based Macrocycles

Huaxi He, Heye Zhou, Bin Liu

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2265-2282 DOI: 10.6023/cjoc202410014

Abstract( 298) HTML( 15) PDF(2451KB)( 743 )

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Advances in the Synthesis of Energetic Derivatives Based on 3-Amino-4-cyanofurazan

Liang Sang, Dongxue Li, Ming Lu, Yuangang Xu

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2283-2312 DOI: 10.6023/cjoc202411017

Abstract( 228) HTML( 5) PDF(2337KB)( 180 )

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Magnetic Functional Material: An Efficient Catalyst for Preparing Biodiesel

Juan Qu, Anguo Ying

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2313-2325 DOI: 10.6023/cjoc202412006

Abstract( 109) HTML( 4) PDF(9061KB)( 112 )

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Application of Manganese Catalysts in Coupling Reactions in Organic Synthesis

Chao Wang, Hongping Chen, Mingzhong Mi, Aowen Li, Yan Qi, Yongjun Liu

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2326-2334 DOI: 10.6023/cjoc202412002

Abstract( 206) HTML( 9) PDF(685KB)( 291 )

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Construction of Cysteine Fluorescent Probes and Their Applications in Pathological Examination

Zhaozhou Li, Yafang Xie, Jian Tao, Xuebing Wei, Lele Li, Yajuan Li, Jiamin Tang, Huawei Niu, Xiujin Chen, Hongli Gao, Fang Li, Huichun Yu, Yunxia Yuan, Shaobin Gu, Huaibin Kang, Xiaofei Sun, Guoyan Ren, Ying Wu

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2335-2349 DOI: 10.6023/cjoc202410024

Abstract( 154) HTML( 3) PDF(11095KB)( 102 )

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Recent Advances in the Synthesis and Applications of Isothiocyanates

Zunqi Liu, Jahangir Khan, Muhammad Akram, Yasir Mumtaz

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2350-2366 DOI: 10.6023/cjoc202410008

Abstract( 365) HTML( 9) PDF(752KB)( 476 )

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Recent Advances in the Transformation Reactions of Aryl Ethers via C—OMe Bond Cleavage

Yiming Shen, Dong Zou

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2367-2388 DOI: 10.6023/cjoc202410023

Abstract( 263) HTML( 6) PDF(1318KB)( 2424 )

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Recent Advances in Photosensitizers of Heteroleptic Tris(cyclometalated) Iridium Complexes

Qian Shi, Zhongyu Li, Han Li

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2389-2405 DOI: 10.6023/cjoc202410017

Abstract( 309) HTML( 9) PDF(3015KB)( 216 )

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ARTICLES

Synthesis and Activity of Benzenesulfonyl Piperazines

Jiangyu Liu, Hongtao Liu, Yexiang Wu, Guosheng Zhang, Yujie Wang, Yuhao Zhang, Lijuan Lei, Yanni Xu, Wenyan Li

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2406-2415 DOI: 10.6023/cjoc202409007

Abstract( 221) HTML( 17) PDF(6264KB)( 182 )

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Mechanochemical Synthesis of (2-Hydroxyphenyl)(3- quinolinyl)ketone

Qiuling Xu, Ruifen Sun, Junliang Wang, Xiaoshan He

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2416-2424 DOI: 10.6023/cjoc202411009

Abstract( 177) HTML( 1) PDF(560KB)( 142 )

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One-Pot Synthesis of Symmetrical Diselenides via Nano-CuO Catalysis through Aryl Iodides with Se⁰

Shuxiao Feng, Xuan Zhong, Jiahao Chen, Zongluo Zhang, Guangna Gu, Junling Wang, Yafei Guo, Junying Ma, Shouren Zhang

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2425-2434 DOI: 10.6023/cjoc202411011

Abstract( 131) HTML( 5) PDF(3713KB)( 69 )

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Study on the Borylation of β-C Positions of Aryl Olefins Catalyzed by Copper Organophosphorus Complexes

Shunli Du, Yaya Wang, Jiaming Guo, Xuewei Xu, Xinhua Peng

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2435-2443 DOI: 10.6023/cjoc202410022

Abstract( 113) HTML( 4) PDF(644KB)( 61 )

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Study on Synthesis and Properties of New Indeno[2,1-b]fluorene-5,7-dione Derivatives

Jing Wang, Yuxun Chen, Jingjing Jiang

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2444-2450 DOI: 10.6023/cjoc202412016

Abstract( 96) HTML( 5) PDF(1065KB)( 37 )

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Cobalt(II)-Catalyzed Asymmetric Hydrogen Transfer Reactions of Ketones

Minhao Li, Zeming Wang, Qing Huang, Weiwei Zuo

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2451-2460 DOI: 10.6023/cjoc202412023

Abstract( 115) HTML( 7) PDF(3431KB)( 62 )

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Retro-Claisen Reaction of α-Allyl-1,3-diketones Catalyzed by Brønsted Acid

Liangxia Wang, Changming Xu

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2461-2468 DOI: 10.6023/cjoc202411023

Abstract( 108) HTML( 2) PDF(602KB)( 51 )

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Ring Opening Reaction between Donor Acceptor (D-A) Cyclopropane and β-Aminketone

Yin Zhang, Rui Zhang, Wenjuan Li

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2469-2479 DOI: 10.6023/cjoc202411003

Abstract( 291) HTML( 1) PDF(722KB)( 184 )

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A Pillar[5]arene-Based π-Conjugated Dye Used for Fluorescence Sensing of L-Arginine

Xiaopeng Ling, Shaoping Tao, Qi Lin, Bingbing Shi, Hong Yao, Taibao Wei, Jinfa Chen

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2480-2485 DOI: 10.6023/cjoc202411015

Abstract( 198) HTML( 1) PDF(4004KB)( 79 )

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Staurosporine Natural Products Derived from Marine Streptomyces sp. OUCMDZ-5522

Shutian Bu, Yong Wang, Wenjian Yin, Qingyun Wen, Pei Wang, Weiming Zhu

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2486-2500 DOI: 10.6023/cjoc202411022

Abstract( 146) HTML( 1) PDF(1555KB)( 106 )

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Rhodium Catalyzed Insertion Reaction of Diazothiooxindoles for Construction of Benzothiophene Derivatives

Xiaoyuan Cui, Fang Jin, Xin Huang, Tao Qin, Congbin Ji

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2501-2508 DOI: 10.6023/cjoc202411013

Abstract( 229) HTML( 0) PDF(564KB)( 97 )

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Synthesis, Photophysical Properties, and Reactive Oxygen Species Generation Mechanism of Type I and Type II D-π-A Hemicyanine Photosensitizers

Weiguang Zhang, Guofeng Zhang, Meng Li, Xuelian Li, Shuhong Bao, Lixiao Ge, Zhiping Shi, Qiangqiang Shen, Li Yao, San E Zhu

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2509-2519 DOI: 10.6023/cjoc202411024

Abstract( 192) HTML( 4) PDF(1922KB)( 368 )

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Visible Light-Mediated Iridium-Catalyzed Debromocyclization of Aliphatic α-Bromotrifluoromethyl Groups

Ting Mao, Linyuan Zeng, Jilin Wen, Jia Jia

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2520-2528 DOI: 10.6023/cjoc202409018

Abstract( 182) HTML( 10) PDF(837KB)( 215 )

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Cesium Carbonate-Promoted Hydrocyanide Reaction of N-(Quinolin-8-yl)but-3-enamides and Trimethylsilyl Cyanide

Xiaolong Zhu, Jing Cui, Runsheng Zeng

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2529-2536 DOI: 10.6023/cjoc202409043

Abstract( 157) HTML( 1) PDF(535KB)( 101 )

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TfOH-Catalyzed O—H Insertion of Carboxylic Acids with α-Aryl Diazoesters

Guifang Chen, Hongqiang Li, Xingrong Zeng

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2537-2544 DOI: 10.6023/cjoc202410026

Abstract( 123) HTML( 1) PDF(490KB)( 126 )

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Intramolecular Charge Transfer Complex Enabled Trifluoromethylation of Heteroarenes with Trifluoromethyl Phosphonium Salt

Shuai Liu, Kunquan Chen, Dequn Sun, Qiang Liu, Xiangyu Chen

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2545-2551 DOI: 10.6023/cjoc202411006

Abstract( 235) HTML( 3) PDF(804KB)( 134 )

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Brønsted Base-Catalyzed Assembly of Sulfochromeno[4,3-b]-pyrrolidines via Michael-Mannich-SuFEx Tandem Reaction of o-Hydroxy Schiff Bases and Vinylsulfonyl Fluorides

Fang Zhang, Pei Xie, Qichao Zhang, Leifang Wu, Lin He, Guangfen Du

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2552-2565 DOI: 10.6023/cjoc202410010

Abstract( 228) HTML( 5) PDF(1026KB)( 203 )

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Design, Synthesis, and Activity Assessment of Fudosteine Derivatives for Chronic Respiratory Disorders

Maoru Sun, Tengyao Gui, Congdi Chen, Hongjun Yang, Xuefeng Li

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2566-2576 DOI: 10.6023/cjoc202409029

Abstract( 187) HTML( 3) PDF(1563KB)( 249 )

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Synthesis and Antitumor Activity of Innovative Homotriazine Compounds

Tiantian He, Lijiao Sun, Jiahui Lü, Jinjing Li, Yonghong Du

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2577-2585 DOI: 10.6023/cjoc202408021

Abstract( 196) HTML( 5) PDF(441KB)( 120 )

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Preparation of α-(Di(alkoxycarbonyl)methyl)chalcones and Their Application in the Synthesis of Multisubstituted Cyclopropanes

Junqiang Jiao, Gaosheng Yang

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2586-2599 DOI: 10.6023/cjoc202408023

Abstract( 64) HTML( 3) PDF(735KB)( 37 )

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Dibenz[b,f]oxepins and Flavonids from Bauhinia variegata var. candida

Dan Huang, Chengbao Duan, Fu Si, Huiping Xie, Hongxing Zhu, Liqin Wang

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2600-2604 DOI: 10.6023/cjoc202412010

Abstract( 137) HTML( 2) PDF(470KB)( 71 )

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Two New Nor-Labdane Diterpenoids from Hedychium spcatum Rhizomes

Luli Shi, Junfang Dong, Qichao Qian, Wenhao Qiao, Weiyan Hu, Laiwei Li, Rongping Zhang, Xinglong Chen

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2605-2611 DOI: 10.6023/cjoc202412008

Abstract( 94) HTML( 0) PDF(2246KB)( 27 )

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Microwave-Assisted Synthesis of 2-Acylamino Naphthothiazole Derivatives

Tianbao Liu, Doudou Miao, Yanfen Peng, Min Zhang, Meifang Gui, Weilong Bi, Yawen Zong

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2612-2619 DOI: 10.6023/cjoc202410021

Abstract( 107) HTML( 0) PDF(529KB)( 68 )

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Three New Phenolic Derivatives from the Fruits of Rubus idaeus Linnaeus and Their Anti-inflammatory Activity

Yu Zhang, Xuefeng Xu, Hao Yan, Decai Dai

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2620-2624 DOI: 10.6023/cjoc202409022

Abstract( 176) HTML( 0) PDF(446KB)( 70 )

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An Efficient Synthetic Route to Erianin

Shuoqi Wang, Chengming Wang

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2625-2629 DOI: 10.6023/cjoc202409009

Abstract( 316) HTML( 8) PDF(824KB)( 191 )

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HIGHLIGHTS

Enantioselective Macrocyclization via Catalytic Metallic Dipole Relay

Jiangtao Wei, Weiping Deng

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2630-2632 DOI: 10.6023/cjoc202500016

Abstract( 73) HTML( 2) PDF(470KB)( 46 )

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Cross-Electrophile Coupling of Aryl Chlorides with Alkyl Chlorides Using Rotating Magnetic Field and Metal Rods

Hong Chang, Shiyi Zhuang, Weiwei Jin

Chinese Journal of Organic Chemistry 2025, 45 (7), pp 2633-2635 DOI: 10.6023/cjoc202500017

Abstract( 90) HTML( 5) PDF(464KB)( 49 )

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