Acta Chimica Sinica ›› 1993, Vol. 51 ›› Issue (10): 1005-1009. Previous Articles     Next Articles

Original Articles

亲水性二苯甲胺树脂制备及用于肽合成研究

程晓辉;阎虎生;倪爱国;何炳林   

  1. 南开大学高分子化学研究所
  • 发布日期:1993-10-15

Preparation of hydrophilic benzhydrylamine resin and its application in solid phase peptide synthesis

CHENG XIAOHUI;YAN HUSHENG;NI AIGUO;HE BINGLIN   

  • Published:1993-10-15

Ester group-contg. polyacrylamide resin was prepared with reverse phase suspension copolymn.; the benzhydrylamine groups were introduced to the polymer by ethylenediamine substitution and two-step condensation. The effect of reaction conditions was studied. With the use of the prepared support, a model peptide was synthesized. Condensation yields in the peptide synthesis were measured. The yields and purity of the peptide were satisfactory.

Key words: SYNTHESIS, POLYACRYLAMIDE, POLYPEPTIDE, HYDROPHILICITY

CLC Number: