The transition metal complexes have been prepared from transition metal nitrate and warfarin- anion sodium and characterized by elemental analysis, IR, UV, thermal analysis, molar conductivity and solubility. Above complexes have a constant composition of NanML3•2H2O (L＝warfarinanion, n＝0, 1) by different synthesized methods. The transition metal complexes all show anticoagulant action in related experiments. And the anticoagulant action of the metal complexes with warfarinanion and salicylate has been compared.The transition metal complexes have been prepared from transition metal nitrate and warfarin- anion sodium and characterized by elemental analysis, IR, UV, thermal analysis, molar conductivity and solubility. Above complexes have a constant composition of NanML3•2H2O (L＝warfarinanion, n＝0, 1) by different synthesized methods. The transition metal complexes all show anticoagulant action in related experiments. And the anticoagulant action of the metal complexes with warfarinanion and salicylate has been compared.

Key words: transition metal, complex, warfarinanion, anticoagulant action