Three new lignan compounds named Schisanlignone A(4), B(5) and butyryl binankadsurin A(6) along with three known lignans, binankadsurin A(1), acetyl binankadsurin A(2) and angeloyl binankadsurin A(3), were isolated from the seeds of a kadsura sp. collected in Rongshui county of Guangxi, China. Their structure elucidation including absolute configurations relies on chemical conversions of 4 into (+)-deoxyschizandrin (4a), of 5 into 4, and of 6 into 1 besides the routine spectral analysis. 4 and 5 show a significant activity against Leukaema P-388 cell (IC~5~0 10 and 40μ g/mL respectively) in vitro.

Key words: SEPARATION, STRUCTURE, SPECTROGRAPHIC ANALYSIS, LEUKEMIA, ANTICARCINOGEN