有机化学 ›› 2006, Vol. 26 ›› Issue (11): 1529-1532. 上一篇    下一篇

研究论文

雷公藤新三萜成分的研究

杨光忠*,a,李春玉b,李援朝b   

  1. (a中南民族大学生命科学学院民族药物研究所 武昌 430074)
    (b中国科学院上海生命科学院上海药物所 上海 201203)
  • 收稿日期:2005-12-06 修回日期:1900-01-01 发布日期:2006-10-27
  • 通讯作者: 杨光忠

Study of a New Triterpenoid from Tripterygium wilfordii

YANG Guang-Zhong*,a,LI Chun-Yub,LI Yuan-Chaob   

  1. (a National Medicine Institute, College of Life Sciences, South-Central University for Nation-alities, Wuchang 430074)
    (b Shanghai Institute of Materia Medica, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences,
    Shanghai 201203)
  • Received:2005-12-06 Revised:1900-01-01 Published:2006-10-27
  • Contact: YANG Guang-Zhong

研究雷公藤(Tripterygium wilfordii Hook. f.)根心部分的化学成分. 采用硅胶柱色谱法进行分离, 从其氯仿提取物中分离得1个三萜化合物, 经光谱分析(HREIMS, 1H NMR, 13C NMR, HMBC, HMQC, NOESY)鉴定其结构为3β,22β-dihydroxy-29-nor-D:A-friedoolean-21-one-2β,24-lactone.

关键词: 三萜, 卫矛科, 雷公藤

To study the active principles of Tripterygium wilfordii Hook. f., a new triterpenoid was isolated from root xylem of this plant by column chromatography on silica gel. Its structure was identified as 3β,22β- dihydroxy-29-nor-D:A-friedoolean-21-one-2β,24-lactone.

Key words: Tripterygium wilfordii, triterpenoid, celastraceae