有机化学 ›› 2013, Vol. 33 ›› Issue (07): 1527-1531.DOI: 10.6023/cjoc201305005 上一篇    下一篇

研究简报

绿色合成抗癫痫药氯西加酮及其类似物

刘改枝a, 吴亚a, 徐海伟b, 刘宏民b   

  1. a 河南中医学院药学院 郑州 450046;
    b 郑州大学药学院 郑州 450001
  • 收稿日期:2013-05-03 修回日期:2013-05-24 发布日期:2013-07-23
  • 通讯作者: 刘改枝, 刘宏民
  • 基金资助:

    河南中医学院博士基金(No. BSJJ2010-03)资助项目.

A Green Route for the Synthesis of Antiepileptic Drug Losigamone and Its Analogues

Liu Gaizhia, Wu Yaa, Xu Haiweib, Liu Hongminb   

  1. a Henan University of Traditional Chinese Medicine, Zhengzhou 450046;
    b School of Pharmaceutical Science, Zhengzhou University, Zhengzhou 450001
  • Received:2013-05-03 Revised:2013-05-24 Published:2013-07-23
  • Supported by:

    Project supported by the Doctoral Research Foundation of Henan University of Traditional Chinese Medicine (No. BSJJ2010-03).

关键词: 绿色合成, 氯西加酮, 合成, 抗癫痫药, 非对映选择性

Key words: green synthesis, losigamone, synthesis, anticonvulsive activity, diastereoselectivity