有机化学 ›› 2015, Vol. 35 ›› Issue (4): 743-759.DOI: 10.6023/cjoc201411028 上一篇    下一篇

研究专题

氧化偶联反应的最新研究进展

张剑a, 陆庆全a, 刘超a, 雷爱文a,b   

  1. a 武汉大学化学与分子科学学院 高等研究院 武汉 430027;
    b 江西师范大学国家单糖化学合成工程技术研究中心 南昌 330022
  • 收稿日期:2014-11-14 修回日期:2015-01-24 出版日期:2015-04-25 发布日期:2015-01-28
  • 通讯作者: 雷爱文 E-mail:aiwenlei@whu.edu.cn
  • 基金资助:

    科技部973计划(Nos. 2012CB725302, 2011CB808600)、国家自然科学基金(Nos. 21390400, 21272180, 21302148)、高等学校博士学科点专项科研基金资助(No. 20120141130002)、教育部长江学者和创新团队发展计划(No. IRT1030)、国家科学技术部基金(No. 2012YQ120060)、高等学校学科创新引智计划(111项目)资助项目.

Recent Advances in Oxidative Coupling Reactions

Zhang Jiana, Lu Qingquana, Liu Chaoa, Lei Aiwena,b   

  1. a College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan 430072;
    b National Research Center for Carbohydrate Synthesis, Jiangxi Normal University, Nanchang 330022
  • Received:2014-11-14 Revised:2015-01-24 Online:2015-04-25 Published:2015-01-28
  • Supported by:

    Project supported by the 973 Program (Nos. 2012CB725302, 2011CB808600), the National Natural Science Foundation of China (Nos. 21390400, 21272180, and 21302148), and the Research Fund for the Doctoral Program of Higher Education of China (No. 20120141130002), the Program for Changjiang Scholars and Innovative Research Team in University (No. IRT1030), the Ministry of Science and Technology of China (No. 2012YQ120060) and the Program of Introducing Talents of Discipline to Universities of China (111 Program).

近年来, 过渡金属催化的氧化偶联反应已成为有机合成化学中构建碳—碳键以及各类碳—杂键的重要方法. 主要综述了我们研究小组在氧化偶联领域, 尤其是第三代氧化偶联反应方面所取得的研究进展, 介绍了各类反应的特点、优势及在合成中的应用.

关键词: 氧化偶联, 氧化羰基化, 氧化酯化, 亲核试剂

Recently, transition-metal-catalyzed oxidative coupling reactions have emerged as the most important and attractive methods to construct carbon-carbon bond and carbon-heteroatom bonds in organic synthetic chemistry. This review mainly summarizes our research progress in the area of oxidative coupling and their versatility, application in organic synthesis, especially for the third generation of oxidative coupling.

Key words: oxidative coupling, oxidative carbonylation, oxidative esterification, nuclephiles