有机化学 ›› 2018, Vol. 38 ›› Issue (4): 760-774.DOI: 10.6023/cjoc201708048 上一篇    下一篇

所属专题: 荧光探针-生物传感合辑 有机超分子化学合辑

综述与进展

L-半胱氨酸可视化传感器/体系的研究进展

王军a, 虎良军b, 申婧a, 姜吉泉a, 郁科勇a, 孙荣国a   

  1. a 贵州师范大学化学与材料科学学院 贵阳 550001;
    b 铜仁市第二中学 铜仁 554300
  • 收稿日期:2017-08-23 修回日期:2017-11-15 发布日期:2017-12-01
  • 通讯作者: 王军 E-mail:beyoundme@126.com
  • 基金资助:

    贵州省科技厅联合基金(No.[2015]7774)、贵州省教育厅青年科技人才成长基金(No.[2016]141)、贵州省科技厅社会发展攻关计划(No.[2015]3014)及贵州师范大学博士启动基金资助项目.

Research Progress in the Visual Sensors/Sensing Ensembles for L-Cysteine

Wang Juna, Hu Liangjunb, Shen Jinga, Jiang Jiquana, Yu Keyonga, Sun Rongguoa   

  1. a College of Chemistry and Material Science, Guizhou Normal University, Guiyang 550001;
    b No.2 Middle School of Tongren, Tongren 554300
  • Received:2017-08-23 Revised:2017-11-15 Published:2017-12-01
  • Contact: 10.6023/cjoc201708048 E-mail:beyoundme@126.com
  • Supported by:

    Project supported by the Joint Funds of Science and Technology of Guizhou Province (No.[2015]7774), the Growth Project for Youth Science and Technology Talent of Education Department of Guizhou Province (No.[2016]141), the Social Development Program of Science and Technology Department of Guizhou Province (No.[2015]3014) and the Doctor's Initial Funding of Guizhou Normal University.

由于L-半胱氨酸(Cysteine,Cys)在病理生理学以及临床医学等学科领域的重要性,Cys的高选择性检测长期以来受到高度关注.重点综述2010年至今可视化检测Cys的传感器/体系,并根据传感机制的不同分为反应型单分子传感器以及基于金属配合物和纳米材料的传感体系.还简单展望了Cys传感器/体系的发展趋势.

关键词: 半胱氨酸, 可视化检测, 传感器, 传感体系, 纳米粒子

Methods for optical detection or sensing of L-cysteine with high selectivity and sensitivity have attracted increasing interest recently due to the potential association of L-cysteine to the fields of pathophysiology and clinical medicine. Recent advances since 2010 on reaction-based small molecule sensors as well as sensing ensembles constructed by metal complex and nanomaterials for optical sensing of L-cysteine were highlighted. The future advances in this field were also predicted and given at the end of this review.

Key words: cysteine, visual detection, sensor, sensing ensemble, nanoparticle