Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (11): 2389-2392.DOI: 10.6023/cjoc201506029 Previous Articles     Next Articles



蒋晓军a, 申雅靓b, 刘泽龙b, 吕绪良a, 涂涛b   

  1. a 解放军理工大学野战工程学院 南京 210007;
    b 复旦大学化学系 上海 200433
  • 收稿日期:2015-06-24 修回日期:2015-07-09 发布日期:2015-08-17
  • 通讯作者: 吕绪良, 涂涛;
  • 基金资助:

    教育部博士点基金(No. 20130071110032)、上海市带头学科(No. B108)及复旦大学卓学资助项目.

Acenaphthoimidazole N-Heterocyclic Carbene Palladium ComplexesCatalyzed Cyanation Reactions in Aqueous Accelerated byMicrowave Irradiation

Jiang Xiaojuna, Shen Yajingb, Liu Zelongb, Lü Xulianga, Tu Taob   

  1. a College of Field Engineering, PLA University of Science and Technology, Nanjing 210007;
    b Department of Chemistry, Fudan University, Shanghai 200433
  • Received:2015-06-24 Revised:2015-07-09 Published:2015-08-17
  • Supported by:

    Project supported by the Research Fund of Doctoral Program, Ministry of Education (No. 20130071110032), the Shanghai Leading Academic Discipline Project (B108) and the Department of Chemistry Fudan University.

In the presence of acenaphthoimidazole N-heterocyclic carbene palladium complexes, cyanation of aryl bromides by non-toxic and inexpensive potassium hexacyanoferrate (II) as cyanide source in water has been investigated under microwave conditions. Both electron-donating and electron-withdrawing groups attached to the substrates show unobvious effects on the transformation and produce the corresponding products in good to excellent yields within few minutes, which demonstrate the practicability and environmentally friendliness of the new developed protocol.

Key words: cyanation, N-heterocyclic carbene, microwave assistant, palladium, aqueous phase