Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (5): 954-961.DOI: 10.6023/cjoc201512014 Previous Articles     Next Articles



韦丽, 陈绪文, 刘云云, 万结平   

  1. 江西师范大学化学化工学院 南昌 330022
  • 收稿日期:2015-12-07 修回日期:2016-01-10 发布日期:2016-01-15
  • 通讯作者: 万结平
  • 基金资助:


Recent Advances in Organic Synthesis Employing Ethyl Lactate as Green Reaction Medium

Wei Li, Chen Xuwen, Liu Yunyun, Wan Jieping   

  1. College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022
  • Received:2015-12-07 Revised:2016-01-10 Published:2016-01-15
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21562025) and the Natural Science Foundation of Jiangxi Province (No. 20151BAB203008).

The biomass-derivable ethyl lactate has been attracting daily increasing attention as a green medium in organic synthesis. The unique advantages of nontoxicity, low cost, complete biodegradability, high boiling point, and excellent compatibility to water and most organic compounds of this solvent cater well to the property of a green reaction medium. In recent years, ethyl lactate (EL) has been successfully used as medium in different types of organic reactions, including Suzuki-Miyaura reaction, Glaser reaction as well as cascade synthesis of heterocyclic compounds with biological activities. Based on our own research interest in this issue, the advances in organic synthesis employing EL as a green medium are summarized.

Key words: green medium, ethyl lactate, coupling reaction, condensation reaction, cascade reaction