Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (10): 2496-2498.DOI: 10.6023/cjoc201604012 Previous Articles     Next Articles



肖世基a, 徐德林a, 付少彬a, 张茂生a, 丁立生b, 周燕b   

  1. a 遵义医学院药学院 遵义 563003;
    b 中国科学院成都生物研究所 成都 610041
  • 收稿日期:2016-04-06 修回日期:2016-05-08 发布日期:2016-06-02
  • 通讯作者: 肖世基,
  • 基金资助:


Two New Nitrogen Compounds from Gymnotheca involucrata

Xiao Shijia, Xu Delina, Fu Shaobina, Zhang Maoshenga, Ding Lishengb, Zhou Yanb   

  1. a School of Pharmacy, Zunyi Medical University, Zunyi 563003;
    b Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041
  • Received:2016-04-06 Revised:2016-05-08 Published:2016-06-02
  • Supported by:

    Project supported by the National Natural Sciences Foundation of China (No.31560102).

By silica gel, MCI column chromatographic and preparative HPLC (high performance liquid chromatography) technologies, six nitrogen compounds were isolated from the whole parts of Gymnotheca involucrata. By using spectroscopic techniques including NMR and MS, these compounds were identified as 2-(1-hydroxy-6-methoxy-4-oxocyclohexa-2-ene- 1-yl)acetonitrile (1), 10-methoxy-1-oxa-3-azaspiro[4.5]dec-2,6-diene-8-one (2), 2-(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)- acetonitrile (3), 1-oxa-3-azaspiro[4.5]dec-2-ene-8-one (4), 1-oxa-3-azaspiro[4.5]dec-2,6-diene-8-one (5) and 4-hydroxybenzyl acetonitrile (6). Compounds 1 and 2 are new compounds, compound 3 is a new natural product, and compounds 4~6 were isolated from this plant for the first time.

Key words: Gymnotheca involucrata, saururaceae, nitrogen compound, chemical constituent