Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (6): 1556-1559.DOI: 10.6023/cjoc201612003 Previous Articles     Next Articles



郭芳杰, 何雨轩, 王景芸, 孙京, 周明东   

  1. 辽宁石油化工大学化学与材料科学学院 抚顺 113001
  • 收稿日期:2016-12-02 修回日期:2017-01-14 发布日期:2017-02-17
  • 通讯作者: 孙京,周明东,
  • 基金资助:


Potassium tert-Butoxide Promoted Formation of Alkyl Aryl Thioethers at Room Temperature: Synthesis and Mechanism

Guo Fangjie, He Yuxuan, Wang Jingyun, Sun Jing, Zhou Mingdong   

  1. School of Chemistry and Materials Science, Liaoning Shihua University, Fushun 113001
  • Received:2016-12-02 Revised:2017-01-14 Published:2017-02-17
  • Contact: 10.6023/cjoc201612003,
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21101085), the Natural Science Foundation of Liaoning Province (No. 2015020196), the Fushun Science & Technology Program (No. FSKJHT 201423), the Liaoning Excellent Talents Program in University (No. LJQ2012031), and the Talent Scientific Research Fund of Liaoning Shihua University (No. 2016XJJ-006).

The C—S cross-coupling of aryl halides with alkyl thiols under transition metal-free conditions was investigated. Good to excellent yields can be obtained for a variety of electron-poor aryl halides with alkyl thiols in the presence of KOtBu even at room temperature. The mechanisms for transition metal-free coupling reactions are discussed.

Key words: C—S cross-coupling, aryl halides, mechanism, alkyl aryl thioethers