Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (7): 1849-1854.DOI: 10.6023/cjoc201711041 Previous Articles     Next Articles

Special Issue: 碳氢活化合辑2018-2019



王少凡a, 赵启鹏a, 王国栋b, 王凯b, 夏成才b   

  1. a 宁夏医科大学药学院 银川 750004;
    b 泰山医学院药学院 泰安 271016
  • 收稿日期:2017-11-22 修回日期:2018-01-28 发布日期:2018-03-08
  • 通讯作者: 夏成才
  • 基金资助:


Palladium-Catalyzed Direct o-Nitrification of Azobenzenes with Co(NO3)2·6H2O via C-H Activation

Wang Shaofana, Zhao Qipenga, Wang Guodongb, Wang Kaib, Xia Chengcaib   

  1. a School of Pharmacy, Ningxia Medical University, Yinchuan 750004;
    b Pharmacy College, Taishan Medical University, Tai'an 271016
  • Received:2017-11-22 Revised:2018-01-28 Published:2018-03-08
  • Contact: 10.6023/cjoc201711041
  • Supported by:

    Project supported by the Projects of Medical and Health Technology Development Program in Shandong Province (No. 2015WS0102).

An efficient protocol for conversion of azobenzenes into their ortho-nitro derivatives via palladium-catalyzed C-H bond activation has been developed. Commercially available and less expensive Co(NO3)2·6H2O was used as the nitrification reagent. Various o-nitroazobenzenes were obtained in excellent yields.

Key words: C-H activation, azobenzenes, Co(NO3)2·6H2O, nitrification