Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (10): 2666-2672.DOI: 10.6023/cjoc201804030 Previous Articles     Next Articles

Special Issue: 有机光催化合辑



方洁梅, 范为正, 冯柏年   

  1. 江南大学药学院 无锡 214122
  • 收稿日期:2018-04-16 修回日期:2018-05-22 发布日期:2018-06-06
  • 通讯作者: 冯柏年,
  • 基金资助:


Visible-Light Catalyzed Trifluoroethylation of Propiolates to Synthesize Coumarin Analogues

Fang Jiemei, Fan Weizheng, Feng Bainian   

  1. School of Pharmaceutical Science, Jiangnan University, Wuxi 214122
  • Received:2018-04-16 Revised:2018-05-22 Published:2018-06-06
  • Contact: 10.6023/cjoc201804030
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21302066).

A practical strategy has been described for the preparation of trifluoroethyl-coumarin derivatives using a visible-light-promoted trifluoroethylation reaction of propiolate with trifluoroethyl iodide. These reactions could be carried out at room temperature in good chemical yields with good functional group tolerance.

Key words: photocatalyst, propiolate, trifluoroethylation