Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (2): 350-362.DOI: 10.6023/cjoc201806038 Previous Articles     Next Articles

Special Issue: 镍催化有机反应合辑



李娅琼, 范玉航, 贾乾发   

  1. 长江师范学院化学化工学院 重庆 408100
  • 收稿日期:2018-06-24 修回日期:2018-07-30 发布日期:2018-09-10
  • 通讯作者: 贾乾发
  • 基金资助:


Recent Advance in Ni-Catalyzed Reductive Cross-Coupling to Construct C(sp2)-C(sp2) and C(sp2)-C(sp3) Bonds

Li Yaqiong, Fan Yuhang, Jia Qianfa   

  1. College of Chemistry and Chemical Engineering, Yangtze Normal University, Chongqing 408100
  • Received:2018-06-24 Revised:2018-07-30 Published:2018-09-10
  • Contact: 10.6023/cjoc201806038
  • Supported by:

    Project supported by the Yangtze Normal University (No. 2017KYQD24).

The cross-coupling of two electrophiles has emerged as an important and attractive method for carbon-carbon bond formation. This synthetic protocol avoids preparation of organometallic nucleophilic reagents and exhibits excellent functional group tolerance. Recently, breakthrough progress has been developed to the cross-electrophile coupling of C(sp2)-X/C(sp3)-X. The recent progress in the research of Ni-catalyzed electrophilic coupling for the construction of C(sp2)-C(sp2) and C(sp2)-C(sp3) is reviewed.

Key words: cross-coupling reaction, reductive coupling, electrophiles, Ni catalysis