Chinese Journal of Organic Chemistry ›› 2019, Vol. 39 ›› Issue (12): 3588-3593.DOI: 10.6023/cjoc201905028 Previous Articles     Next Articles


杨森a, 丁成荣a, 刘幸海a, 翁建全a, 袁静b, 谭成侠a   

  1. a 浙江工业大学化学工程学院 杭州 310014;
    b 浙江农林大学林业与生物技术学院 杭州 311300
  • 收稿日期:2019-05-13 修回日期:2019-06-03 发布日期:2019-06-19
  • 通讯作者: 袁静, 谭成侠;
  • 基金资助:

Synthesis and Herbicidal Activity of Chiral Aryloxyphenoxypropionic Amides Compounds

Yang Sena, Ding Chengronga, Liu Xinghaia, Weng Jianquana, Yuan Jingb, Tan Chengxiaa   

  1. a College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014;
    b College of Forestry and Biotechnology, Zhejiang Agriculture and Forestry University, Hangzhou 311300
  • Received:2019-05-13 Revised:2019-06-03 Published:2019-06-19
  • Supported by:
    Project supported by the National Key R & D Program (No. 2017YFD0200507).

In order to find pesticidal lead compounds with high herbicidal activity, a series of novel chiral aryloxyphenoxypropionic amides were designed and synthesized using the principle of active substructure combination and the technology of biological enzyme splitting. The structures of the target compounds were confirmed by 1H NMR and HRMS. The preliminary bioassay data showed that all target compounds displayed excellent herbicidal activity and selectivity against monocotyledonous weeds. At the dosage of 150 g/ha, the target compounds showed herbicidal activity against Backmannia syzigachne, Polypogon fugax and Poa acroleuca with more than 75%. And the control effects of three compounds against Polypogon fugax Nees were 100%.

Key words: aryloxyphenoxypropionic acids, herbicide, chirality, herbicidal activity, synthesize, enzyme splitting