Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (7): 2153-2158.DOI: 10.6023/cjoc202002014 Previous Articles     Next Articles


姚明a, 张静静a,b, 杨森a, 熊航行a,b   

  1. a 荆楚理工学院化工与药学院 湖北荆门 448000;
    b 武汉工程大学化工与制药学院 武汉 430205
  • 收稿日期:2020-02-13 修回日期:2020-03-27 发布日期:2020-04-13
  • 通讯作者: 姚明, 熊航行;
  • 基金资助:
    湖北省教育厅优秀中青年创新团队项目基金(No. T201719)资助项目.

γ-Aluminum Oxide-Mediated Iodination of Terminal Alkynes

Yao Minga, Zhang Jingjinga,b, Yang Sena, Xiong Hangxinga,b   

  1. a College of Chemical Engineering and Pharmacy, Jingchu University of Technology, Jingmen, Hubei 448000;
    b School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan 430205
  • Received:2020-02-13 Revised:2020-03-27 Published:2020-04-13
  • Supported by:
    Project supported by the Science Technology Foundation for Creative Research Group of Hubei Department of Education (No. T201719).

A simple two-step, one-pot synthesis of 1,2,2-triiodovinyl derivatives from terminal alkynes using N-iodosuc-cinimide and iodine as precursors, activated with γ-aluminum oxide is developed. This approach resulted in moderate to excellent yields, good functional group tolerance and utilization of an inexpensive catalyst.

Key words: terminal alkyne, iodination, aluminum oxide, 1,2,2-triiodovinyl derivative, one-pot process