Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (12): 4639-4650.DOI: 10.6023/cjoc202107022 Previous Articles     Next Articles

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芳基偶氮砜的芳基化及砜基化研究进展

孟娜a, 刘启顺a, 刘瑞生a, 吕玉芬a,*(), 赵晓辉b,*(), 魏伟a,b,*()   

  1. a 曲阜师范大学化学与化工学院 山东曲阜 273165
    b 中国科学院西北高原生物研究所 中国科学院藏药研究重点实验室 青海西宁 810008
  • 收稿日期:2021-07-07 修回日期:2021-07-29 发布日期:2021-08-09
  • 通讯作者: 吕玉芬, 赵晓辉, 魏伟
  • 作者简介:
    † 共同第一作者
  • 基金资助:
    山东省高校青创科技计划(2019KJC021); 2018中国科学院“西部之光”人才培养引进计划资助项目

Recent Advances in Arylations and Sulfonylations of Arylazo Sulfones

Na Menga, Qishun Liua, Ruisheng Liua, Yufen Lüa(), Xiaohui Zhaob(), Wei Weia,b()   

  1. a School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, Shandong 273165
    b Key Laboratory of Tibetan Medicine Research, Chinese Academy of Sciences, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, Qinghai 810008
  • Received:2021-07-07 Revised:2021-07-29 Published:2021-08-09
  • Contact: Yufen Lü, Xiaohui Zhao, Wei Wei
  • About author:
    † These authors contributed equally to this work.
  • Supported by:
    Youth Innovation and Technology Project of Higher School in Shandong Province(2019KJC021); 2018 CAS "Light of West China" Program

Aromatic ring- and sulfone-containing compounds are widely used in the fields of synthetic chemistry, medicinal chemistry and material chemistry. Therefore, it is of great significance to develop a simple, green and efficient method to construct aryl and sulfonyl compounds. Arylazo sulfones can be used as arylation or sulfonylation reagents to access aryl and sulfonyl compounds via hemolytic cleavage of C—N and N—S bonds to generate aryl radical and sulfonyl radical. In this review, the recent research progress of arylations and sulfonylations using arylazo sulfones is summarized. The synthetic methods and the related reaction mechanisms are highlighted, and an outlook of this research field is also given.

Key words: arylazo sulfones, photocatalysis, electrocatalytic, arylations, sulfonylations